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  • GPT-5-Codex-Mini – A more compact and cost-efficient version of GPT-5-Codex(github.com)
    52 points by wahnfrieden 2 days ago | 52 comments
  • Phase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3(nejm.org)
    6 points by libpcap 16 hours ago | 1 comment
  • Iran faces unprecedented drought as water crisis hits Tehran(bbc.com)
    61 points by FridayoLeary 11 hours ago | 80 comments
  • I analyzed the lineups at the most popular nightclubs(dev.karltryggvason.com)
    164 points by kalli 4 days ago | 87 comments
  • Valkey 9.0: innovation, features, and improvements(valkey.io)
    8 points by tamnd a day ago | discuss
  • HTML Slides with notes(nbd.neocities.org)
    87 points by Curiositry 3 days ago | 43 comments
  • Expansive view of the Milky Way reveals our galaxy in unprecedented radio colour(icrar.org)
    9 points by geox 21 hours ago | discuss
  • A Plan for 5-10%* Faster Free-Threaded JIT by Python 3.16(fidget-spinner.github.io)
    6 points by signa11 7 hours ago | discuss
  • Show HN: Three Emojis, a daily word puzzle for language learners(threeemojis.com)
    31 points by knuckleheads 3 days ago | 26 comments
  • Peter Thiel: Capitalism Isn't Working for Young People(thefp.com)
    28 points by gscott a day ago | 33 comments
  • How often does Python allocate?(zackoverflow.dev)
    106 points by ingve 9 days ago | 78 comments
  • Farmers' Almanac will cease publication(washingtonpost.com)
    7 points by paulpauper 14 hours ago | 1 comment
  • Carice TC2 – A non-digital electric car(caricecars.com)
    298 points by RubenvanE 5 days ago | 206 comments
  • A File Format Uncracked for 20 Years(landaire.net)
    59 points by signa11 3 days ago | 13 comments
  • Ask HN: Why do designers have repugnant websites?(undefined)
    13 points by admissionsguy a day ago | 8 comments
  • Microsoft's data sovereignty: Now with extra sovereignty!(theregister.com)
    13 points by sipofwater a day ago | discuss
  • Show HN: TabPFN-2.5 – SOTA foundation model for tabular data(priorlabs.ai)
    72 points by onasta 4 days ago | 12 comments
  • FBI tries to unmask owner of archive.is(heise.de)
    999 points by Projectiboga 4 days ago | 504 comments
  • Sidney Reilly(en.wikipedia.org)
    7 points by georgecmu 17 hours ago | discuss
  • Analysis of Hedy Lamarr's Contribution to Spread-Spectrum Communication(researchers.one)
    66 points by drmpeg 3 days ago | 49 comments
  • Many would-be buyers are frozen out of the housing market(npr.org)
    7 points by pseudolus 14 hours ago | 2 comments
  • Oxy is Cloudflare's Rust-based next generation proxy framework (2023)(blog.cloudflare.com)
    191 points by Garbage 7 days ago | 88 comments
  • How to Keep Winning(amasad.me)
    57 points by daviducolo 7 days ago | 27 comments
  • AMD warns the Intel and Nvidia partnership is a risk to its business(tomshardware.com)
    5 points by mgh2 10 hours ago | discuss
  • Launch HN: Plexe (YC X25) – Build production-grade ML models from prompts(plexe.ai)
    85 points by vaibhavdubey97 6 days ago | 31 comments
  • Scientists find ways to boost memory in aging brains(news.vt.edu)
    177 points by stevenjgarner 3 days ago | 55 comments
  • Machine Scheduler in LLVM – Part II(myhsu.xyz)
    31 points by mshockwave 8 days ago | discuss
  • Ask HN: My family business runs on a 1993-era text-based-UI (TUI). Anybody else?(undefined)
    312 points by urnicus 5 days ago | 306 comments
  • Cloudflare tells U.S. govt that foreign site blocking efforts are trade barriers(torrentfreak.com)
    326 points by iamnothere 4 days ago | 212 comments
  • Valori – A Python-native Vector Database I built from scratch(undefined)
    8 points by varshith17 a day ago | 9 comments