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Risk of dementia following gabapentin prescription(rapm.bmj.com)
13 points by geox 19 hours ago | 7 comments
  • stacktrust16 hours ago

    Earlier thread (50 comments), https://news.ycombinator.com/item?id=44527484

  • codingdave19 hours ago

    Correlation.

    I take gabapentin for pain, so this study absolutely caught my eye. And I'm going to ask my doc about it. But the study is clear that this is a correlation, not a causation.

    • jjgreen19 hours ago |parent

      True, but tendency to dementia causes a fondness for a particular drug? Some 3rd effect causes both?

      • codingdave19 hours ago |parent

        Those questions are exactly why I'm going to ask my doc. But because gabapentin is specifically for neuropathic pain, I could certainly envision a scenario where a deeper neurological root cause is giving someone both pain and dementia, so they are both symptoms.

        I'm not banking on that, of course. It is worth digging into to find out more.

        • stacktrust18 hours ago |parent

          https://news.ycombinator.com/item?id=44527484#44529281

        • jjgreen19 hours ago |parent

          Definitely, best of luck ...

      • sudoshred18 hours ago |parent

        Another plausible interpretation is that the profile of a patient who is commonly prescribed the drug substantially overlaps with the profile of a patient who one day develops dementia.